Naltrexone improves learning and attention in self-injurious individuals with developmental disabilities

Self-injurious Behavior among Individuals with Intellectual and Developmental Disabilities

Self-injurious behavior (SIB) is a broad term describing a behavior that causes (or potentially produces) physical harm to oneself. This behavior is described in individuals intellectual and developmental disabilities, including those with autism. SIB is a severe clinical condition that produces serious medical consequences and limits life opportunities for the persons and those who care for th...

Naltrexone decreases self-injurious behavior.

The effect of naltrexone (0.5, 1.0, 1.5, and 2.0 mg/kg) on the frequency of self-injurious behavior (SIB) was investigated in three male adolescents. The frequency of total SIB was reduced significantly in all three subjects; dose-dependent decreases (at 0.5, 1.0, and 1.5 mg/kg) in SIB frequency were observed in the two mentally retarded subjects. These data suggest a role for opioid peptides i...

Self-injurious Behaviour 1 Running head: SELF-INJURIOUS BEHAVIOUR The Relationship between Stereotyped Movements and Self-Injurious Behaviour in Children with Developmental or Sensory Disabilities

The relationship between stereotyped movements and self-injurious behavior in children with developmental or sensory disabilities.

We assessed whether the stereotyped movements (SM) that are a defining characteristic of autism are discriminable from those observed in other disorders, and whether stereotyped self-injurious movements, which are excluded as exemplars of SM in DSM-IV, differ from other SM in severity or in kind. We used the Stereotyped and Self-Injurious Movement Interview to assess self-injurious and other SM...

Stereotyped behaviors predicting self-injurious behavior in individuals with intellectual disabilities.

We examined the relation between stereotyped behavior and self-injurious behavior (SIB) for 1871 individuals with intellectual disabilities who had a score of >0 on the Behavior Problem Inventory (BPI-01; Rojahn et al., 2001). We report three main findings: First, structural equation modeling techniques (SEM) revealed that the BPI-01stereotyped behavior subscale scores predicted BPI-01 SIB subs...